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If phenobarbital and doxycycline are administered concurrently, the clinical response to doxycycline need to be monitored closely.The more lipid soluble the barbiturate, the more speedily it penetrates all tissues of the body. Barbiturates are sure to plasma and tissue proteins to a different diploma with the diploma of binding, rising specifically
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Phenobarbital Sodium Injection contains the preservative benzyl alcohol and isn't advisable to be used in neonates. There have been experiences of deadly ‘gasping syndrome’ in neonates (children fewer than 1 thirty day period of age) adhering to the administration of intravenous answers made up of the preservative benzyl alcohol.Anticoagulants.
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